Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 356025Generated: October 30, 2026

6-Chloroindole → 6-Chloro-2,3-dihydro-1h-indole

https://huagongshe.com/reaction/356025

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloroindoleHCID 87111—
ReactantSodium cyanoborohydrideHCID 5003444—
SolventAcetic AcidHCID 176—
Product6-Chloro-2,3-dihydro-1h-indoleHCID 25856794%

Reaction Steps

6-Chloroindole was reduced in the usual way with sodium cyanoborohydride in glacial acetic acid to give the title compound (D36) (1.18 g, 94%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05834494
Source datasetuspto-grants-1998_11
ORD IDord-d4b0d1e06866444e9c8afa2d0de73390
Source noteuspto-grants-1998_11