3-Isocyanatopyridine → 5-Phenyl-1-(3-pyridylcarbamoyl)indoline

HRID 356048Notes

Reaction equation

HRID 356048 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([N:7]=[C:8]=[O:9])[CH:2]=1.[C:10]1([C:16]2[CH:17]=[C:18]3[C:22](=[CH:23][CH:24]=2)[NH:21][CH2:20][CH2:19]3)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[C:10]1([C:16]2[CH:17]=[C:18]3[C:22](=[CH:23][CH:24]=2)[N:21]([C:8](=[O:9])[NH:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[CH2:20][CH2:19]3)[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 27604933-IsocyanatopyridineHCID 134974755-phenyl-2,3-dihydro-1H-indole

Product 1

HCID 108528285-Phenyl-1-(3-pyridylcarbamoyl)indoline

Procedure

The title compound was prepared as in the method of (Example 2) from 3-pyridyl isocyanate and 5-phenylindoline (D30) to give (E15) (0.73 g, 52%) m.p. 241°-2° C.

Workup

  1. customto give (E15) (0.73 g, 52%) m.p. 241°-2° C.

Sources & evidence

ORD record
ord-6c3690987fa54b95b40f95bb5c9634fd
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

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