3-Isocyanatopyridine → 6,7-dichloro-N-(pyridin-3-yl)indoline-1-carboxamide

HRID 356050Notes

Reaction equation

HRID 356050 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([N:7]=[C:8]=[O:9])[CH:2]=1.[Cl:10][C:11]1[C:19]([Cl:20])=[C:18]2[C:14]([CH2:15][CH2:16][NH:17]2)=[CH:13][CH:12]=1>>[Cl:10][C:11]1[C:19]([Cl:20])=[C:18]2[C:14]([CH2:15][CH2:16][N:17]2[C:8](=[O:9])[NH:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 27604933-IsocyanatopyridineHCID 167882966,7-dichloro-2,3-dihydro-1H-indole

Product 1

HCID 105908916,7-dichloro-N-(pyridin-3-yl)indoline-1-carboxamide

Procedure

The title compound was prepared as in the method of (Example 2) from 3-pyridylisocyanate and 6,7-dichloroindoline (D34) to give (E17) (0.84 g, 46%) m.p. 178°-180° C.

Workup

  1. customto give (E17) (0.84 g, 46%) m.p. 178°-180° C.

Sources & evidence

ORD record
ord-72ff03337f0a40aa8259d92551bab4ea
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

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