6-Chloro-2,3-dihydro-1h-indole → HCID 10730997, compound

HRID 356052Notes

Reaction equation

HRID 356052 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([N:7]=[C:8]=[O:9])[CH:2]=1.[Cl:10][C:11]1[CH:19]=[C:18]2[C:14]([CH2:15][CH2:16][NH:17]2)=[CH:13][CH:12]=1>>[Cl:10][C:11]1[CH:19]=[C:18]2[C:14]([CH2:15][CH2:16][N:17]2[C:8](=[O:9])[NH:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 2585676-Chloro-2,3-dihydro-1h-indoleHCID 27604933-Isocyanatopyridine

Product 1

HCID 10730997HCID 10730997, compound

Procedure

The title compound was prepared as in the method of (Example 2) from 3-pyridylisocyanate and 6-chloroindoline (D36) to give (E19) (1.54 g, 73%) m.p. 204°-5° C.

Workup

  1. customto give (E19) (1.54 g, 73%) m.p. 204°-5° C.

Sources & evidence

ORD record
ord-6586395f9f9c43b8a07c0283ccecc8c8
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

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