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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 356054Generated: November 1, 2026

3-Isocyanatopyridine → 5-Trifluoromethyl-1-(3-pyridylcarbamoyl)indoline

https://huagongshe.com/reaction/356054

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-IsocyanatopyridineHCID 2760493—
Reactant5-(trifluoromethyl)-2,3-dihydro-1H-indoleHCID 15447789—
Product5-Trifluoromethyl-1-(3-pyridylcarbamoyl)indolineHCID 10709843—

Reaction Steps

The title compound was prepared as in the method of (Example 2) from 3-pyridylisocyanate and 5-trifluoromethylindoline (D43) to give (E22) (0.12 g, 38%) m.p. 188°-189° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05834494
Source datasetuspto-grants-1998_11
ORD IDord-9fcc26080b174b868f942b230ddbfcd1
Source noteuspto-grants-1998_11