HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isocyanatopyridine → 5-Bromo-N-(pyridin-3-yl)-2,3-dihydro-1H-indole-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isocyanatopyridine | HCID 2760493 | — |
| Reactant | 5-Bromoindoline | HCID 3411566 | — |
| Product | 5-Bromo-N-(pyridin-3-yl)-2,3-dihydro-1H-indole-1-carboxamide | HCID 18940922 | 72% |
Reaction Steps
5-Bromoindoline (D50) (0.5 g, 2.5 mmol) was treated with 3-pyridylisocyanate as in the method of Example 1. The product was filtered-off and recrystallised from methanol/water to afford the title compound (0.58 g, 72%) as a white crystalline solid m.p. 220° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05834494 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-a6adb671d46044fba4d643ddedd28220 |
| Source note | uspto-grants-1998_11 |