3-Isocyanatopyridine → HCID 10830245, compound

HRID 356062Notes

Reaction equation

HRID 356062 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][NH:8]2)=[CH:4][C:3]=1[C:11]([CH3:14])([CH3:13])[CH3:12].[N:15]1[CH:20]=[CH:19][CH:18]=[C:17]([N:21]=[C:22]=[O:23])[CH:16]=1>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][N:8]2[C:22](=[O:23])[NH:21][C:17]2[CH:16]=[N:15][CH:20]=[CH:19][CH:18]=2)=[CH:4][C:3]=1[C:11]([CH3:14])([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 27604933-IsocyanatopyridineHCID 10608491HCID 10608491, compound

Product 1

HCID 10830245HCID 10830245, compoundYield 35%

Procedure

6-Chloro-5-tert-butylindoline (D56) (0.21 g, 1.01 mmol) was treated with 3-pyridylisocyanate as in the procedure described in Example 1. The product was recrystallised from ethanol/diethyl ether to give the title compound (0.12 g, 35%) as a white crystalline solid m.p.=200° C.

Workup

  1. customThe product was recrystallised from ethanol/diethyl ether

Sources & evidence

ORD record
ord-ea4b84b3fdd04bd0bc8629ddaf61bb25
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

Loading…