3-Isocyanatopyridine → HCID 18940889, compound

HRID 356065Notes

Reaction equation

HRID 356065 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][NH:8]2)=[CH:4][C:3]=1[CH:11]=[CH2:12].[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([N:19]=[C:20]=[O:21])[CH:14]=1>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][N:8]2[C:20](=[O:21])[NH:19][C:15]2[CH:14]=[N:13][CH:18]=[CH:17][CH:16]=2)=[CH:4][C:3]=1[CH:11]=[CH2:12]

Participants

3

Reactant 2

HCID 27604933-IsocyanatopyridineHCID 18940906HCID 18940906, compound

Product 1

HCID 18940889HCID 18940889, compound

Procedure

6-Chloro-5-vinylindoline (D62) (0.13 g, crude) was treated with 3-pyridylisocyanate as in the procedure described in Example 1. The crude product was recrystallised from ethanol/diethyl ether to give the title compound (22 mg) as a yellow crystalline solid m.p. 195°-200° C.

Workup

  1. customThe crude product was recrystallised from ethanol/diethyl ether

Sources & evidence

ORD record
ord-a07bbaf35099444ba63d57d2ae10a86b
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Reaction notes

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