HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isocyanatopyridine → 6-Chloro-5-ethylthio-1-(3-pyridylcarbamoyl)indoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isocyanatopyridine | HCID 2760493 | — |
| Reactant | 6-Chloro-5-ethylthioindoline | HCID 18940911 | — |
| Product | 6-Chloro-5-ethylthio-1-(3-pyridylcarbamoyl)indoline | HCID 10404613 | 48% |
Reaction Steps
6-Chloro-5-ethylthioindoline (D64) (0.18 g, 0.85 mmol) was treated with 3-pyridylisocyanate as in the procedure described in Example 1. The crude product was recrystallised from ethanol/diethyl ether to give the title compound (0.14 g, 48%) as a white crystalline solid m.p.=225°-226° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05834494 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-4a19e67e24e4495faf2ab21a30fb5475 |
| Source note | uspto-grants-1998_11 |