Hydrochloric Acid → HCID 18940753, compound

Participants

Reaction Steps

30 ml of 3N methanolic hydrochloric acid are added to a solution of 2.07 g (3.54 mmol) of 1-propyl-9-[2-(2-piperidyl)-ethyl]-1,5,9-tri-BOC-1,5,9-triazanonane in 5 ml of methanol, and the reaction mixture is stirred at room temperature for 15 hours. The crystallisate is filtered off and the filtration residue is suspended in 15 ml of hot methanol. After cooling to room temperature, filtration, washing the crystallizate with ice-cold methanol and drying under a high vacuum at 100° C., the title compound is obtained, m.p. >270° C. 1H-NMR (D2O): δ =0.92(t,3H); 1.41-2.18(m,14H); 2.90-3.42(m,15H).

Provenance & Evidence