Methyl iodide → HCID 18941082, compound

HRID 356122Notes

Reaction equation

HRID 356122 reaction equation
[CH3:1][N:2]1[CH2:6][CH2:5][CH:4]([C:7]2[S:8][C:9]3[CH2:18][C:17]4[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=4[C:10]=3[N:11]=2)[CH2:3]1.[CH3:19][I:20]>>[I-:20].[CH3:1][N+:2]1([CH3:19])[CH2:6][CH2:5][CH:4]([C:7]2[S:8][C:9]3[CH2:18][C:17]4[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=4[C:10]=3[N:11]=2)[CH2:3]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 18941099HCID 18941099, compound

Product 1

HCID 18941082HCID 18941082, compound

Procedure

In 2 ml of methyl iodide, 30 mg of 2-(1-methyl-3-pyrrolidinyl)-8H-indeno[1,2-d]thiazole was dissolved, followed by stirring at room temperature for 18 hours. The solvent was evaporated under reduced pressure. The resulting oily substance was crystallized from diethyl ether-chloroform-methanol, whereby 43 mg of 1,1-dimethyl-3-(8H-indeno[1,2-d]thiazol-2-yl)pyrrolidinium iodide was obtained.

Workup

  1. customThe solvent was evaporated under reduced pressure
  2. customThe resulting oily substance was crystallized from diethyl ether-chloroform-methanol

Sources & evidence

ORD record
ord-ff157c1312b54ee8b7aa720f4b046502
Source dataset
uspto-grants-1998_11
Patent number
US05834499

Reaction notes

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