Allyl bromide → HCID 18940612, compound

HRID 356178Notes

Reaction equation

HRID 356178 reaction equation
[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[C:11]([CH3:19])[CH2:10][C:9]1=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:22][CH:23]=[CH2:24]>>[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[C:11]([CH3:19])[CH:10]([CH2:24][CH:23]=[CH2:22])[C:9]1=[O:20])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7841Allyl bromideHCID 18940576HCID 18940576, compound

Product 1

HCID 18940612HCID 18940612, compoundYield 85%

Procedure

Using 1-benzyl-4-methyl-1,3-dihydro-1,5-benzodiazepin-2(2H)-one and 3-bromopropene, the titled compound was synthesized in substantially the same manner as in Working Example 21 as an oily product in a yield of 85%.

Sources & evidence

ORD record
ord-263355a80a6b4cd5b870122ee9422acb
Source dataset
uspto-grants-1998_11
Patent number
US05834463

Reaction notes

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