HCID 18940587, compound → HCID 70113640, compound

HRID 356180Notes

Reaction equation

HRID 356180 reaction equation
[C:1]1([CH2:11][N:12]2[C:18](=[O:19])[CH:17]3[CH2:20][CH2:21][CH2:22][C:16]3=[N:15][C:14]3[CH:23]=[CH:24][CH:25]=[CH:26][C:13]2=3)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1>C(OCC)(=O)C.CCCCCC>[C:1]1([CH2:11][N:12]2[C:18](=[O:19])[C@H:17]3[CH2:20][CH2:21][CH2:22][C@H:16]3[NH:15][C:14]3[CH:23]=[CH:24][CH:25]=[CH:26][C:13]2=3)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 1

HCID 18940587HCID 18940587, compound

Product 1

HCID 70113640HCID 70113640, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 9-(1-naphthylmethyl)-2,3,9,10a-tetrahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one, the titled compound was synthesized in substantially the same manner as in Working Example 24 in a yield of 67%, m.p. 126°-128° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-a195e30bf7914fb7932f921a44697b99
Source dataset
uspto-grants-1998_11
Patent number
US05834463

Reaction notes

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