HCID 18940612, compound → HCID 18940582, compound

HRID 356183Notes

Reaction equation

HRID 356183 reaction equation
[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[C:11]([CH3:19])[CH:10]([CH2:20][CH:21]=[CH2:22])[C:9]1=[O:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(OCC)C>[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[NH:12][CH:11]([CH3:19])[CH:10]([CH2:20][CH:21]=[CH2:22])[C:9]1=[O:23])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 18940612HCID 18940612, compound

Product 1

HCID 18940582HCID 18940582, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Using 1-benzyl-4-methyl-3-(2-propen-1-yl)-1,3-dihydro-1,5-benzodiazepin-2(2H)-one, the titled compound was synthesized in substantially the same manner as in Working Example 24 in a yield of 85%, m.p. 81°-83° C. (diethylether).

Sources & evidence

ORD record
ord-53e546fee7e8454e87e38f2e7b1ca278
Source dataset
uspto-grants-1998_11
Patent number
US05834463

Reaction notes

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