HCID 18940617, compound → HCID 18940549, compound

HRID 356184Notes

Reaction equation

HRID 356184 reaction equation
[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[C:11]([CH3:19])[CH:10]([CH2:20]/[CH:21]=[CH:22]/[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:9]1=[O:29])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(OCC)C>[CH2:1]([N:8]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[NH:12][CH:11]([CH3:19])[CH:10]([CH2:20]/[CH:21]=[CH:22]/[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:9]1=[O:29])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 18940617HCID 18940617, compound

Product 1

HCID 18940549HCID 18940549, compoundYield 77%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Using 1-benzyl-4-methyl-3((E)-3-phenyl-2-propen-1-yl)-1,3-dihydro-1,5-benzodiazepin-2(2H)-one, the titled compound was synthesized by substantially the same procedure as in Working Example 24 in a yield of 77%, m.p. 119°-120° C. (diethyl ether).

Sources & evidence

ORD record
ord-2be0ddaca2fd442ebea825a3e12d01f7
Source dataset
uspto-grants-1998_11
Patent number
US05834463

Reaction notes

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