HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 356206Generated: October 29, 2026
Gamma-Aminobutyric Acid → 4-Phthalimidobutyric acid
https://huagongshe.com/reaction/356206
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Gamma-Aminobutyric Acid | HCID 119 | — |
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Product | 4-Phthalimidobutyric acid | HCID 18411 | 90% |
Reaction Steps
A mixture of crushed phthalic anhydride (18.53 g, 0.125 mol) and 4-aminobutyric acid was heated for 30 minutes at 140° C. The reaction mixture was cooled, and resulting precipitate was recrystallized from methanol-water to give 26.26 g (yield 90%) of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05834463 |
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| Source dataset | uspto-grants-1998_11 |
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| ORD ID | ord-a9b28bdf1deb4673ba4437399af012e6 |
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| Source note | uspto-grants-1998_11 |
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