Aluminium lithium hydride → {1-methyl-1H-pyrrolo[2,3-b]pyridin-2-yl}methanol

Participants

Reaction Steps

A procedure similar to that described in Preparation 2 was repeated, except that 130 mg of ethyl 1-methyl-7-azaindole-2-carboxylate (prepared as described in Preparation 80), 23 mg of lithium aluminum hydride and 2 ml of tetrahydrofuran were used, to give 110 mg of the title compound having Rf=0.47 (on silica gel thin layer chromatography using a 3 1 by volume mixture of hexane and ethyl acetate as the developing solvent).

Provenance & Evidence