反应详情

N-Ethyl-1-methyl-1H-pyrazole-4-carboxamide was prepared from 1-methyl-1H-pyrazole-4-carboxylic acid and 70% ethylamine in water using the methods of steps a and b of Example 248. The product was purified by flash chromatography with 10% ethyl acetate-hexane and recovered as a white solid in 54.7% yield. m.p. 103°-106° C.

1. customThe product was purified by flash chromatography with 10% ethyl acetate-hexane
2. customrecovered as a white solid in 54.7% yield