Methyl acetoacetate → HCID 70251287, compound

Participants

Reaction Steps

The title compound was prepared from [4-(4-methyl-3-oxo-pentyl)-phenyl]-carbamic acid 1,1-dimethylethyl ester obtained in Example PPPPP (2.1 g, 7.2 mmol), methyl acetoacetate (2.1 g, 18.1 mmol), 60% NaH (0.80 g, 20 mmol), and n-butyllithium (14 mL of 1.5M, 21 mmol) in THF as described in General Method 6. The product was carried on crude to the next step.

Provenance & Evidence