HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 17977876, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 17977881 | HCID 17977881 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | tert-Butyl methyl ether | HCID 15413 | — |
| Product | HCID 17977876 | HCID 17977876 | — |
Reaction Steps
37.8 g (0.1 mol) of 4-(2-p-tolylsulfonyloxyethoxy)-phenyl 2-hydroxy-2-propyl ketone (obtained by reacting compound IIa with p-toluenesulfonyl chloride) and 9.8 g (0.15 mol) of sodium azide are stirred for one hour in 100 ml of DMSO at 60° C. Through extractive work-up using water and ether or methyl t-butyl ether, 22.4 g of compound IIf are obtained as a pale yellow, readily mobile oil. IR: v=2114 cm-1 (N3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05837746 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-61032c91b30e4788aaee6195934c9e71 |
| Source note | uspto-grants-1998_11 |