HCID 10581365, compound → HCID 10594394, compound

Participants

Reaction Steps

Compound 5 (0.28 g, 0.32 mmol) was dissolved in 10% CF3COOH in CHCl3 (20 mL) and stirred at room temperature in a stoppered flask for 45 min. The reaction mixture was evaporated to dryness in vacuo, the oily residue was purified by flash chromatography (EtOAc/hexane 5:1, 2 cm×15 cm), appropriate fractions pooled, evaporated to dryness and crystallized from MeOH/H2O to give 85 mg (74%) of compound 7 as white crystals.

Provenance & Evidence