HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 3-[4-(2-Aminopyridin-3-yloxy)butyl]thiazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 2-Amino-3-(4-chlorobutyloxy)pyridine | HCID 18936781 | — |
| Reactant | 2,4-Thiazolidinedione sodium salt | HCID 86738727 | — |
| Product | 3-[4-(2-Aminopyridin-3-yloxy)butyl]thiazolidine-2,4-dione | HCID 18936703 | — |
Reaction Steps
Using 10.06 g (50 mmol) of 2-amino-3-(4-chlorobutyloxy)pyridine, 6.97 g (50 mmol) of thiazolidine-2,4-dione sodium salt and 7.49 g (50 mmol) of sodium iodide, the same procedure as in Reference Example 11 was followed, to yield 9.53 g (67.8%, light yellow oily substance) of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840732 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-1df695eb32874ee8a019d3cfd6b0fba8 |
| Source note | uspto-grants-1998_11 |