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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357020Generated: October 30, 2026

Triethylamine → 5-(4-Chlorobutylthio)-2-methylimidazo[1,2-a]pyridine

https://huagongshe.com/reaction/357020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant1-Bromo-4-chlorobutaneHCID 81364—
ReactantHCID 178429829HCID 178429829—
Product5-(4-Chlorobutylthio)-2-methylimidazo[1,2-a]pyridineHCID 18936662—

Reaction Steps

Using 657 mg (4.0 mmol) of 5-mercapto-2-methylimidazo-[1,2-a]pyridine, 0.70 ml (5.0 mmol) of triethylamine and 0.58 ml (5.0 mmol) of 1-bromo-4-chlorobutane, the same procedure as in Reference Example 1 was followed, to yield 838 mg (82.3%, light orange solid) of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05840732
Source datasetuspto-grants-1998_11
ORD IDord-84030f74c3b84c75a4ee38749cf5c5d7
Source noteuspto-grants-1998_11