Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357046Generated: October 26, 2026

Hydrochloric Acid → 5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochloride

https://huagongshe.com/reaction/357046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dioneHCID 57017637—
SolventMethanolHCID 887—
Product5-Butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione hydrochlorideHCID 70206013—

Reaction Steps

To a solution of 1.29 g (2.92 mmol) of 5-butylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]oxazolidine-2,4-dione in 50 ml of methanol, 0.4 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.29 g (100%, yellow oily substance) of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05840732
Source datasetuspto-grants-1998_11
ORD IDord-ce07c1de6da24e4bb45c70d7411dd0b5
Source noteuspto-grants-1998_11