HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Propylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-Propylidene-3-(4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione | HCID 57293628 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Propylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride | HCID 86753343 | — |
Reaction Steps
To a solution of 1.37 g (3.79 mmol) of 5-propylidene-3-(4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 50 ml of methanol, 0.35 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 1.66 g (100%, yellow oily substance) of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840732 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-d7fbf8f54d604229b9caa460a7e9750e |
| Source note | uspto-grants-1998_11 |