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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357158Generated: October 30, 2026

Hydrochloric Acid → 5-(Ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

https://huagongshe.com/reaction/357158

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-(Ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dioneHCID 54199019—
SolventMethanolHCID 887—
Product5-(Ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochlorideHCID 73472911—

Reaction Steps

To a solution of 0.76 g (1.93 mmol) of 5-(ethylthiomethylene)-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 20 ml of methanol, 0.21 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 0.78 g (94.0%, yellow solid) of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05840732
Source datasetuspto-grants-1998_11
ORD IDord-be8e65d8d7ac414db4a15bedb9dbc3cf
Source noteuspto-grants-1998_11