Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357175Generated: October 30, 2026

Hydrochloric Acid → 5-Nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

https://huagongshe.com/reaction/357175

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dioneHCID 57171626—
SolventMethanolHCID 887—
Product5-Nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochlorideHCID 73472919—

Reaction Steps

To a solution of 1.96 g (4.40 mmol) of 5-nonylidene-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione in 30 ml of methanol, 0.42 ml of concentrated hydrochloric acid was added. After the solvent was distilled off, the residue was washed with diethyl ether to yield 2.01 g (94.8%, yellow-orange oily substance) of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05840732
Source datasetuspto-grants-1998_11
ORD IDord-b2496a958ab249b8918063693c3f13e5
Source noteuspto-grants-1998_11