Hydrogen chloride-ethyl acetate → HCID 70205573, compound

HRID 357198Notes

Reaction equation

HRID 357198 reaction equation
[CH:1](=[C:7]1[O:11][C:10](=[O:12])[N:9]([CH2:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[C:19]3[N:20]([CH:24]=[CH:25][N:26]=3)[CH:21]=[CH:22][CH:23]=2)[C:8]1=[O:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[ClH:28].C(OCC)(=O)C>CO>[ClH:28].[CH:1](=[C:7]1[O:11][C:10](=[O:12])[N:9]([CH2:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[C:19]3[N:20]([CH:24]=[CH:25][N:26]=3)[CH:21]=[CH:22][CH:23]=2)[C:8]1=[O:27])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 57245668HCID 57245668, compound

Product 1

HCID 70205573HCID 70205573, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a methanol solution of 96 mg (0.25 mmol) of 5-hexylidene-3-[4-(imidazo[1,2-a)pyridin-8-yloxy)butyl]oxazolidine-2,4-dione, 0.063 ml of 4N hydrochloric acid-ethyl acetate was added, followed by stirring, after which the solvent was distilled off, to yield 100 mg (98.1%, yellow oily substance) of the desired product.

Workup

  1. distillationafter which the solvent was distilled off

Sources & evidence

ORD record
ord-8de01831fb2a4036b439b76659c8c656
Source dataset
uspto-grants-1998_11
Patent number
US05840732

Reaction notes

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