HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrogen chloride-ethyl acetate → 5-[3-(2-Methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Edukt | 5-[3-(2-Methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione | HCID 56983096 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 5-[3-(2-Methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride | HCID 73472973 | — |
Reaktionsschritte
To a methanol solution of 1.40 g (3.0 mmol) of 5-[3-(2-methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione, 1.0 ml of 4N hydrochloric acid-ethyl acetate was added, followed by stirring, after which the solvent was distilled off, to yield 1.22 g (80.4%, white oily substance) of the desired product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05840732 |
| Quelldatensatz | uspto-grants-1998_11 |
| ORD ID | ord-8f609a5d17964fc9810ed7bb72540c23 |
| Quellennotiz | uspto-grants-1998_11 |