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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 357206Erstellt: 25. Oktober 2026

Hydrogen chloride-ethyl acetate → 5-[3-(2-Methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochloride

https://huagongshe.com/reaction/357206

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrogen chloride-ethyl acetateHCID 21866389—
Edukt5-[3-(2-Methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dioneHCID 56983096—
LösungsmittelMethanolHCID 887—
Produkt5-[3-(2-Methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione hydrochlorideHCID 73472973—

Reaktionsschritte

To a methanol solution of 1.40 g (3.0 mmol) of 5-[3-(2-methoxyphenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione, 1.0 ml of 4N hydrochloric acid-ethyl acetate was added, followed by stirring, after which the solvent was distilled off, to yield 1.22 g (80.4%, white oily substance) of the desired product.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05840732
Quelldatensatzuspto-grants-1998_11
ORD IDord-8f609a5d17964fc9810ed7bb72540c23
Quellennotizuspto-grants-1998_11