Hydrogen chloride-ethyl acetate → HCID 73472894, compound

Participants

Reaction Steps

To a methanol solution of 1.11 g (2.5 mmol) of 5-(3-(2-fluorophenyl)propylidene]-3-[4-(imidazo[1,2-a]pyridin-5-ylthio)butyl]thiazolidine-2,4-dione, 1.0 ml of 4N hydrochloric acid-ethyl acetate was added, followed by stirring. After the solvent was distilled off, the residue was dissolved in methanol and recrystallized from ether to yield 0.94 g (76.8%, white crystal) of the desired product.

Provenance & Evidence