HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Allylhydroxylamine → 2-[(2,6-dichloro-3-methylphenyl)amino]benzaldehyde-O-allyl oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Allylhydroxylamine | HCID 420841 | — |
| Reactant | 2-[(2,6-Dichloro-3-methylphenyl)amino]benzaldehyde | HCID 15027377 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-[(2,6-dichloro-3-methylphenyl)amino]benzaldehyde-O-allyl oxime | HCID 86753357 | 94% |
Reaction Steps
A solution in 3:1 ethanol-pyridine of 2-[(2,6-dichloro-3-methylphenyl)amino]benzaldehyde, prepared as in Example 1, steps 1-2, and O-allyl hydroxylamine(1.3 eq) was heated at reflux for 2 days. The reaction mixture was poured into ethyl acetate and the mixture was extracted with 10% aqueous HCl. Chromatography on silica gel (20% CH2Cl2 /hexanes) gave 2-[(2,6-dichloro-3-methylphenyl)amino]benzaldehyde-O-allyl oxime (1.13 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840758 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-e3fa647ebc19415aaf4056e716c3f77f |
| Source note | uspto-grants-1998_11 |