1-{2-[(2,6-Dichloro-3-methylphenyl)amino]phenyl}ethanol → 2-[(2,6-Dichloro-3-methylphenyl)amino]acetophenone

HRID 357286Notes

Reaction equation

[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[C:4]([Cl:9])[C:3]=1[NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH:17](O)[CH3:18].CC(C)=[O:22].OS(O)(=O)=O.O=[Cr](=O)=O>>[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[C:4]([Cl:9])[C:3]=1[NH:10][CH2:11][C:16]([C:15]1[CH:14]=[CH:13][CH:12]=[CH:17][CH:18]=1)=[O:22]

Participants

Reactant 2

HCID 675606441-{2-[(2,6-Dichloro-3-methylphenyl)amino]phenyl}ethanol

HCID 131709961Jones' reagent

Product 1

HCID 189369812-[(2,6-Dichloro-3-methylphenyl)amino]acetophenone

Procedure

The desired compound was prepared by oxidation of 1-{2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}ethanol, prepared as in step 1, with Jones reagent.

Sources & evidence

ORD record: ord-5f803d3e89c94c86a857823c3f62b62c
Source dataset: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05840758

Reaction notes

Loading…