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HRID357477

反应详情

EQUATION

反应方程式

HRID 357477 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O
HCID6249

Ampicillin

C16H19N3O4S

PRODUCTS

生成物

1
结构：CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O.O.O.O
HCID23565

Ampicillin trihydrate

C16H25N3O7S

PROCEDURE

实验过程

The resultant crude protected ampicillin mixture is worked up by treating with a mixture of ice-water and concentrated HCl. After phase separation the aqueous phase is brought to pH 4.5. The title compound is obtained after filtration and washing with 90% aqueous acetone, followed by drying. Yield 66.34 g=89%. Purity 98.8%.

WORKUP

后处理

  1. customAfter phase separation the aqueous phase