Ethanol → HCID 19600560, compound

HRID 357545Notes

Reaction equation

HRID 357545 reaction equation
[CH3:1][C:2]1[C:7]([CH3:8])=[C:6]([O:9][CH2:10][CH2:11][N:12]2[C:16](=[O:17])[CH2:15][CH2:14][C:13]2=[O:18])[CH:5]=[CH:4][N+:3]=1[O-].C(O)C.[C:23]([O:26]C(=O)C)(=[O:25])[CH3:24]>>[C:23]([O:26][CH2:1][C:2]1[C:7]([CH3:8])=[C:6]([O:9][CH2:10][CH2:11][N:12]2[C:16](=[O:17])[CH2:15][CH2:14][C:13]2=[O:18])[CH:5]=[CH:4][N:3]=1)(=[O:25])[CH3:24]

Participants

4

Reactant 3

HCID 702EthanolHCID 7918Acetic AnhydrideHCID 15166212HCID 15166212, compound

Product 1

HCID 19600560HCID 19600560, compound

Conditions

Temperature
100 °C

Procedure

0.12 g of 2,3-dimethyl-4-(2-succinimidoethoxy)pyridine N-oxide was dissolved in 5 ml of acetic anhydride to obtain a solution. This solution was stirred at 100° C. for 0.5 hour and cooled, followed by the addition of 30 ml of ethanol. The obtained mixture was stirred at a room temperature for 0.5 hour and distilled to remove the solvent. Thus, 0.14 g of crude 2-acetoxymethyl-3-methyl-4-(2-succinimidoethoxy)pyridine was obtained as an oil.

Workup

  1. customto obtain a solution
  2. temperaturecooled
  3. stirringThe obtained mixture was stirred at a room temperature for 0.5 hour
  4. distillationdistilled
  5. customto remove the solvent

Sources & evidence

ORD record
ord-0621cf161ab34da5948324d6a0707f77
Source dataset
uspto-grants-1998_11
Patent number
US05840910

Reaction notes

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