Acetic Anhydride → HCID 53960347, compound

HRID 357548Notes

Reaction equation

HRID 357548 reaction equation
[CH3:1][C:2]1[C:7]([CH3:8])=[C:6]([O:9][CH2:10][CH2:11][O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[CH:5]=[CH:4][N+:3]=1[O-].[C:21]([O:24]C(=O)C)(=[O:23])[CH3:22]>C(O)C>[C:21]([O:24][CH2:1][C:2]1[C:7]([CH3:8])=[C:6]([O:9][CH2:10][CH2:11][O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[CH:5]=[CH:4][N:3]=1)(=[O:23])[CH3:22]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 15166213HCID 15166213, compound

Product 1

HCID 53960347HCID 53960347, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
100 °C

Procedure

A mixture comprising 0.60 g of 2,3-dimethyl-4-(2-pyridylmethoxyethoxy)pyridine N-oxide and acetic anhydride was stirred at 100° C. for 0.5 hour and cooled, followed by the addition of 40 ml of ethanol. The obtained mixture was stirred at a room temperature for 0.5 hour and distilled to remove the solvent. The residue was dried in a vacuum to obtain 0.47 g of crude 2-acetoxymethyl-3-methyl-4-(2-pyridylmethoxyethoxy)pyridine as an oil.

Workup

  1. temperaturecooled
  2. stirringThe obtained mixture was stirred at a room temperature for 0.5 hour
  3. distillationdistilled
  4. customto remove the solvent
  5. customThe residue was dried in a vacuum

Sources & evidence

ORD record
ord-bd46ded9d47b4df6ad1609ece0dec97b
Source dataset
uspto-grants-1998_11
Patent number
US05840910

Reaction notes

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