HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357552Generated: October 29, 2026
Sodium Hydroxide → HCID 178488131, compound
https://huagongshe.com/reaction/357552
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-Chloromethyl-4-(2-hydroxyethoxy)-3-methylpyridine | HCID 15166222 | — |
| Reactant | HCID 178488140 | HCID 178488140 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178488131 | HCID 178488131 | 90.1% |
Reaction Steps
60 ml of ethanol was added to a mixture comprising 0.7 g of 2-chloromethyl-4-(2-hydroxyethoxy)-3-methylpyridine, 0.63 g of 2-mercapto-5-methoxy-1H-benzimidazole and 0.16 g of sodium hydroxide to obtain a mixture. This mixture was stirred at 60° C. for one hour, concentrated and purified by silica gel column chromatography to obtain 1.08 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05840910 |
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| Source dataset | uspto-grants-1998_11 |
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| ORD ID | ord-19ead0493f354d9e9a4ae0c540f07863 |
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| Source note | uspto-grants-1998_11 |
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