反应详情

A solution of 16.2 g (0.1 mol) of benzaldehyde guanylhydrazone and 11.8 g (0.050 mol) of 3-methoxyphenacyl bromide (Aldrich, Buchs, Switzerland; 98 %, Cat. no. 11,567-3) in 50 ml of ethanol is stirred at 20° C. for 3 hours. The product that has crystallized out is filtered off with suction and dried. In that manner there is obtained the title compound, m.p. 170°-171° C., 1H-NMR (DMSO): δ=8.56 (s, 1H); 8.03 (s, 1H); 7.92 (m, 2H); 7.5 (m, 3H); 7.26 (m, 3H); 6.76 (m, 1H); 6.2 (s, 2H); 3.8 (s, 3H).

1. customThe product that has crystallized out
2. filtrationis filtered off with suction
3. customdried