HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → Homoveratrylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 3,4-Dimethoxybenzeneacetonitrile | HCID 66727 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | Homoveratrylamine | HCID 8421 | — |
Reaction Steps
DE-A-33 38 681 discloses the catalytic hydrogenation of veratryl cyanide with a ten-fold molar excess of methylamine on a nickel catalyst. Homoveratrylamine is obtained as byproduct with more than 3% selectivity and has to be removed by adding benzaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840981 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-379695e877ce426b9993d04751af77c1 |
| Source note | uspto-grants-1998_11 |