O-ethylhydroxylamine hydrochloride → 2-[1-(Ethoxyimino)butyl]-3-hydroxy-5-(3-hydroxymethyl-2,4,6-trimethylphenyl)cyclohex-2-en-1-one

HRID 35780Notes

Reaction equation

HRID 35780 reaction equation
[C:1]([C:6]1[C:7](=[O:24])[CH2:8][CH:9]([C:13]2[C:18]([CH3:19])=[CH:17][C:16]([CH3:20])=[C:15]([CH2:21][OH:22])[C:14]=2[CH3:23])[CH2:10][C:11]=1[OH:12])(=O)[CH2:2][CH2:3][CH3:4].Cl.[CH2:26]([O:28][NH2:29])[CH3:27]>>[CH2:26]([O:28][N:29]=[C:1]([C:6]1[C:7](=[O:24])[CH2:8][CH:9]([C:13]2[C:18]([CH3:19])=[CH:17][C:16]([CH3:20])=[C:15]([CH2:21][OH:22])[C:14]=2[CH3:23])[CH2:10][C:11]=1[OH:12])[CH2:2][CH2:3][CH3:4])[CH3:27]

Participants

3

Reactant 2

HCID 76850O-ethylhydroxylamine hydrochlorideHCID 178450319HCID 178450319, compound

Product 1

HCID 1361402292-[1-(Ethoxyimino)butyl]-3-hydroxy-5-(3-hydroxymethyl-2,4,6-trimethylphenyl)cyclohex-2-en-1-one

Procedure

2-[1-(Ethoxyimino)butyl]-3-hydroxy-5-(3-hydroxymethyl-2,4,6-trimethylphenyl)cyclohex-2-en-1-one (51) was prepared from 2-butyryl-3-hydroxy-5-(3-hydroxymethyl-2,4,6-trimethylphenyl)cyclohex-2-en-1-one and ethoxyamine hydrochloride following essentially the same procedure as that described in Example 1, part (iv).

Sources & evidence

ORD record
ord-c9dfe726b8ed497881d13040ab88080b
Source dataset
uspto-grants-1988_08
Patent number
US04767879

Reaction notes

Loading…