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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 357900Generated: October 29, 2026

N-[1-(2-phenylethyl)-4-ethoxycarbonyl-5-bromopyrazol-3-yl]-N-[(2'-(N-triphenylmethyl-(1H-tetrazol-5-yl))biphenyl-4-yl)methyl]-n-propylamine → HCID 178457033, compound

https://huagongshe.com/reaction/357900

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[1-(2-phenylethyl)-4-ethoxycarbonyl-5-bromopyrazol-3-yl]-N-[(2'-(N-triphenylmethyl-(1H-tetrazol-5-yl))biphenyl-4-yl)methyl]-n-propylamineHCID 22103828—
SolventEthanolHCID 702—
ProductHCID 178457033HCID 17845703387.7%

Reaction Steps

356 mg of N-[1-(2-phenylethyl)-4-ethoxycarbonyl-5-bromopyrazol-3-yl]-N-[(2'-(N-triphenylmethyl-(1H-tetrazol-5-yl))biphenyl-4-yl)methyl]-n-propylamine were dissolved in 5 ml of ethanol and heated under reflux for 2 hours, and the solvent was distilled off under reduced pressure. The resulting residue was subjected to silica gel column chromatography (n-hexane-ethyl acetate=2:1→ethyl acetate) to obtain 224 mg of the intended compound as a pale yellow, amorphous solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05840909
Source datasetuspto-grants-1998_11
ORD IDord-5718daef5e7148ac9709d70052b12127
Source noteuspto-grants-1998_11