Hydrogen Bromide → HCID 70471019, compound

Participants

Reaction Steps

Optical isomer A of methyl 2-acetylamino-6-methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate (3.45 g., 12.5 mM) was added to 48% w/v aqueous hydrobromic acid (34 ml.). The mixture was stirred and refluxed for 4 hr. The mixture was cooled, whereupon the product crystallised. It was collected by filtration and washed with ethyl acetate. The solid was dried in vacuo at 60° to give optical isomer A of 2-amino-6-hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid hydrobromide.

Provenance & Evidence