Ethyl orthoformate → HCID 20449981, compound

HRID 358056Notes

Reaction equation

HRID 358056 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][CH:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])[C:6]=2[CH:21]=1.[CH:22](OCC)(OCC)OCC>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]3[CH:22]=[N:13][N:12]=[C:10]3[CH2:9][CH:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])[C:6]=2[CH:21]=1

Participants

3

Reactant 2

HCID 31214Ethyl orthoformateHCID 20449995HCID 20449995, compound

Product 1

HCID 20449981HCID 20449981, compound

Procedure

In analogy to Example 16(b), by reacting 7-chloro-5-(2-chlorophenyl)-2-hydrazino-3H-1-benzazepine with triethyl orthoformate there is obtained 8-chloro-6-(2-chlorophenyl)-4H-s-triazolo[4,3-a][1]benzazepine of melting point 189°-190°.

Sources & evidence

ORD record
ord-60439d4dd33d4503a2537fa909632f1a
Source dataset
uspto-grants-1984_08
Patent number
US04464300

Reaction notes

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