Ethyl orthoformate → HCID 20450015, compound

HRID 358057Notes

Reaction equation

HRID 358057 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][CH:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[C:6]=2[CH:20]=1.[CH:21](OCC)(OCC)OCC>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]3[CH:21]=[N:13][N:12]=[C:10]3[CH2:9][CH:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[C:6]=2[CH:20]=1

Participants

3

Reactant 2

HCID 31214Ethyl orthoformateHCID 20449963HCID 20449963, compound

Product 1

HCID 20450015HCID 20450015, compound

Procedure

In analogy to Example 16(b), by reacting 7-bromo-2-hydrazino-5-(2-pyridyl)-3H-1-benzazepine with triethyl orthoformate there is obtained 8-bromo-6-(2-pyridyl)-4H-s-triazolo[4,3-a][1]benzazepine of melting point 219°.

Sources & evidence

ORD record
ord-85ea2e4ba5f441a5b645e8f88ffaec07
Source dataset
uspto-grants-1984_08
Patent number
US04464300

Reaction notes

Loading…