Water → 3-Benzoylbenzaldehyde

HRID 358116Notes

Reaction equation

HRID 358116 reaction equation
[C:1]([C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][OH:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cr](O)(O)(=O)=O.O>CC(C)=O>[C:1]([C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=[O:13])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 962WaterHCID 24425Chromic AcidHCID 127837393-(Hydroxymethyl)benzophenone

Product 1

HCID 130201683-Benzoylbenzaldehyde

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

3-Benzoylbenzyl alcohol (2.0 g) in acetone (10 ml) was treated dropwise at 15°-20° C. with chromic acid solution. After stirring for 5 minutes, water (50 ml) was added and the mixture extracted with ether. The ethereal solution was washed with saturated Na2CO3, saturated NaCl, dried (Na2SO4), evaporated and distilled; b.p. 160°-170° C./0.08 mm, (1.1 g).

Workup

  1. extractionthe mixture extracted with ether
  2. washThe ethereal solution was washed with saturated Na2CO3, saturated NaCl
  3. dry with materialdried (Na2SO4)
  4. customevaporated
  5. distillationdistilled

Sources & evidence

ORD record
ord-e31d2c8775634808a7dcbf3afd28363e
Source dataset
uspto-grants-1984_08
Patent number
US04464391

Reaction notes

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