反应详情

3-Benzoylbenzaldehyde (1.0 g) in dioxan (5 ml) was treated with water (2.5 ml) and sodium cyanide (0.5 g). The whole was cooled below 15° C. and 40% sulphuric acid (1.4 ml) added dropwise (care being taken to ensure that this temperature was not exceeded). Stirring was continued for 1 hour when water (30 ml) was added and the product extracted with methylene chloride and washed with water, saturated NaCl, dried over Na2SO4 and evaporated.

1. temperatureThe whole was cooled below 15° C.
2. extractionthe product extracted with methylene chloride
3. washwashed with water, saturated NaCl
4. dry with materialdried over Na2SO4
5. customevaporated