HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → HCID 88721266, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | HCID 131713652 | HCID 131713652 | — |
| Product | HCID 88721266 | HCID 88721266 | — |
Reaction Steps
In the manner described in Example 11, 3.883 g of 3-acetoxymethyl-7β-[(2S)-2-(4-BOC-aminophenyl)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-acetamido]-3-cephem-4-carboxylic acid diphenylmethyl ester are reacted with 1.75 g of p-toluenesulphonic acid monohydrate in 30 ml of acetonitrile and worked up. 3-Acetoxymethyl-7β-[(2S)-2-(4-aminophenyl)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-acetamido]-3-cephem-4-carboxylic acid diphenylmethyl ester p-toluenesulphonate is obtained. [α]D20 =+32°±1° (0.90% in CH3OH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04464366 |
| Source dataset | uspto-grants-1984_08 |
| ORD ID | ord-9a091d4ea6c04ea19602a477d3d84d83 |
| Source note | uspto-grants-1984_08 |