Phenyl isocyanate → HCID 20449513, compound

HRID 358219Notes

Reaction equation

HRID 358219 reaction equation
[NH2:1][C:2]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([C:13]([OH:15])=[O:14])[CH:8]=2)[N:3]=1.[C:16]1([N:22]=[C:23]=[O:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C(Cl)(Cl)Cl>[C:13]([C:9]1[CH:8]=[C:7]([N:4]2[CH2:5][CH2:6][C:2]([NH:1][C:23]([NH:22][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[O:24])=[N:3]2)[CH:12]=[CH:11][CH:10]=1)([OH:15])=[O:14]

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 609479HCID 609479, compound

Product 1

HCID 20449513HCID 20449513, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

3-Amino-1-(3-carboxyphenyl)-2-pyrazoline (108 mg) and phenylisocyanate (140 mg) in chloroform (10 ml) were heated to reflux overnight. The resultant solid was collected and dried to yield 1-(3-carboxyphenyl)-3-(3-phenylureido)-2-pyrazoline m.p. 255° decomp.

Workup

  1. temperatureto reflux overnight
  2. customThe resultant solid was collected
  3. customdried

Sources & evidence

ORD record
ord-cac78fb5d9e845e397e5ddf4d98ea4ec
Source dataset
uspto-grants-1984_08
Patent number
US04465685

Reaction notes

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