Diethyl Ether → HCID 178484242, compound

HRID 358260Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[CH:10][NH:11][CH:12]=2)=[CH:4][CH:3]=1.C(OCC)C.C(O[CH:21](OCC)[N:22]([CH3:24])[CH3:23])C>>[CH3:21][N:22]([CH3:24])[CH:23]=[N:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[CH:10][NH:11][CH:12]=2)=[CH:6][CH:7]=1

Participants

Reactant 3

HCID 3283Diethyl Ether

HCID 70913Dimethylformamide diethylacetal

HCID 178507418HCID 178507418, compound

Product 1

HCID 178484242HCID 178484242, compound

Procedure

A solution of 3.18 gm of 4-(4-aminophenyl)-1-H-imidazole in 8.82 gm of N,N-dimethyl-formamide diethyl acetal was stirred at room temperature for two days. Addition of diethyl ether resulted in precipitation of the formamidine, which was collected by filtration.

Sources & evidence

ORD record: ord-cabb1d9358204bde80a9339443e24e38
Source dataset: uspto-grants-1984_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04465841

Reaction notes

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