[(6,7-Dichloro-2-cyclopentyl-2-methyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]acetic acid → 6,7-Dichloro-2-cyclopentyl-5-hydroxy-2-methylindan-1-one

Participants

Reaction Steps

A 19.5 g. sample of (+) [(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)-oxy]acetic acid is added to stirred molten (190° C.) pyridine hydrochloride, stirred for 1 hour then poured into ice water (800 ml). The (+)6,7-dichloro-2-cyclopentyl-2,3-dihydro--5-hydroxy-2-methyl-1H-inden-1-one, which separates is filtered, rinsed with water and dried.

Provenance & Evidence