Water → HCID 11105470, compound

HRID 358323Notes

Reaction equation

HRID 358323 reaction equation
[NH2:1][CH2:2][CH:3]([NH2:5])[CH3:4].[CH3:6][C:7]([CH3:11])(O)[C:8]#N.[OH2:12]>CC(C)=O>[CH3:6][C:7]1([CH3:11])[NH:1][CH2:2][CH:3]([CH3:4])[NH:5][C:8]1=[O:12]

Participants

5

Reactant 3

HCID 962Water2×HCID 6406Acetone CyanohydrinHCID 6567Propylenediamine

Product 1

HCID 11105470HCID 11105470, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In a manner analogous to that described in U.S. Pat. No. 2,920,077, 148.3 g (2 moles) of 1,2-diaminopropane and about 500 ml water are placed in a 2-liter 3-necked flask. While stirring, 170.2 g (2moles) of acetone cyanohydrin in 100 ml water are added in 20 min. The reaction is allowed to proceed at 80°-92° C. for 24 hr then water and unreacted materials are removed at 15 mm Hg. The residue, which formed a solid on standing, when dissolved in acetone and recrystallized was found to melt at 115°-117°.

Workup

  1. customwater and unreacted materials are removed at 15 mm Hg
  2. customThe residue, which formed a solid
  3. customrecrystallized
  4. customto melt at 115°-117°

Sources & evidence

ORD record
ord-a22290aee58f4e37b86cae0d5e51c36c
Source dataset
uspto-grants-1984_08
Patent number
US04466916

Reaction notes

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